C118P Suppresses Gastric Cancer Growth via Promoting Autophagy–Lysosomal Degradation of RAB1A

C118P Suppresses Gastric Cancer Growth via Promoting Autophagy–Lysosomal Degradation of RAB1A

<b>Background/Objectives</b>: Gastric cancer (GC) is the leading cause of cancer-related deaths worldwide. C118P, a microtubule inhibitor with anti-angiogenic and vascular-disrupting activities, was proven to be cytotoxic to various cancer cell lines. This study aimed to explore the anti...

Full description

Saved in:
Bibliographic Details
Main Authors: Shihui Wei, Jing Zhang, Hai Wu, Zhengguang Liao, Zhengrui Liu, Yuhang Hou, Danyu Du, Jingwei Jiang, Li Sun, Shengtao Yuan, Mei Yang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceutics
Subjects:
C118P
RAB1A
mTOR
protein degradation
gastric cancer
Online Access:https://www.mdpi.com/1999-4923/16/12/1620
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1999-4923/16/12/1620

Similar Items