Chronic intermittent hypoxia disrupts protective microgliosis in ischemic proliferative retinopathy

Chronic intermittent hypoxia disrupts protective microgliosis in ischemic proliferative retinopathy

Abstract Sleep apnea that leads to chronic intermittent hypoxia (CIH) is an independent risk factor for advanced, debilitating ischemic proliferative retinopathies, such as diabetic retinopathy (DR) and retinopathy of prematurity (ROP). The underlying mechanisms are unknown. Here we investigated the...

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Bibliographic Details
Main Authors: Tianxiang Yang, Kaitryn E. Ronning, Sébastien Augustin, Frédéric Blond, Caroline Nous, Foteini Argyriou, Sara Touhami, Cécile Delarasse, Xavier Guillonneau, Florian Sennlaub
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Neuroinflammation
Subjects:
Hypoxia
Ischemic retinopathy
Microglia
Sleep apnea
Online Access:https://doi.org/10.1186/s12974-025-03392-9
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https://doi.org/10.1186/s12974-025-03392-9

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