Effect of Maternal Hyperglycemia on Fetal Pancreatic Islet Development

Effect of Maternal Hyperglycemia on Fetal Pancreatic Islet Development

Hyperglycemia during fetal development disturbs extracellular matrix (ECM) synthesis and deposition patterns, which disrupts organogenesis and adult organ function. Although the ECM cooperates in pancreas development, little is known about the effects of hyperglycemia on the pancreatic ECM during de...

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Bibliographic Details
Main Authors: Carina Pereira Dias, Michel Raony Teixeira Paiva de Moraes, Fernanda Angela Correia Barrence, Camila Stephanie Balbino da Silva, Basilio Smuckzec, Fernanda Ortis, Telma Maria Tenório Zorn
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biology
Subjects:
diabetes mellitus
extracellular matrix
fetal reprogramming
Online Access:https://www.mdpi.com/2079-7737/14/6/728
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