MEGF9 prevents lipopolysaccharide-induced cardiac dysfunction through activating AMPK pathway

MEGF9 prevents lipopolysaccharide-induced cardiac dysfunction through activating AMPK pathway

Objective: Inflammation and oxidative damage play critical roles in the pathogenesis of sepsis-induced cardiac dysfunction. Multiple EGF-like domains 9 (MEGF9) is essential for cell homeostasis; however, its role and mechanism in sepsis-induced cardiac injury and impairment remain unclear.Methods: A...

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Bibliographic Details
Main Authors: Zhili Jin, Xianqing Li, Huixia Liu, Tao He, Wanli Jiang, Li Peng, Xiaoyan Wu, Ming Chen, Yongzhen Fan, Zhibing Lu, Di Fan, Hairong Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Redox Report
Subjects:
LPS-induced cardiac dysfunction
inflammation
oxidative damage
AMPK
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2024.2435252
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https://www.tandfonline.com/doi/10.1080/13510002.2024.2435252

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