Single-cell RNA sequencing reveals a B cell-related immunosuppressive landscape and a potential suppressor in hepatocellular carcinoma
Abstract Background The sophisticated tumour microenvironment is responsible for the malignant progression and poor prognosis of hepatocellular carcinoma (HCC). Discovering new therapeutic targets is desired for the preferable treatment of HCC patients. Methods To characterize the HCC microenvironme...
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| Main Authors: | Wenhao Hou, Jiaqi Jiang, Liyuan Zhu, Hongwei Xu, Lihui Zhu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-025-06869-6 |
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