The EMC acts as a chaperone for membrane proteins

Abstract Structure formation of membrane proteins is error-prone and thus requires chaperones that oversee this essential process in cell biology. The ER membrane protein complex (EMC) is well-defined as a transmembrane domain (TMD) insertase. In this study, we characterize an additional chaperone f...

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Bibliographic Details
Main Authors: Carolin J. Klose, Kevin M. Meighen-Berger, Martin Kulke, Marina Parr, Barbara Steigenberger, Martin Zacharias, Dmitrij Frishman, Matthias J. Feige
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62109-x
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