Heat shock protein 90 is a chaperone regulator of HIV-1 latency.

An estimated 32 million people live with HIV-1 globally. Combined antiretroviral therapy suppresses viral replication but therapy interruption results in viral rebound from a latent reservoir mainly found in memory CD4+ T cells. Treatment is therefore lifelong and not curative. Eradication of this v...

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Bibliographic Details
Main Authors: Somaya Noorsaeed, Nawal AlBurtamani, Ahmed Rokan, Ariberto Fassati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012524
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