Vaccination with Plasmids Encoding the Fusion Proteins D-S1, D-S1N and O-SN from SARS-CoV-2 Induces an Effective Humoral and Cellular Immune Response in Mice

Vaccination with Plasmids Encoding the Fusion Proteins D-S1, D-S1N and O-SN from SARS-CoV-2 Induces an Effective Humoral and Cellular Immune Response in Mice

Background: Next-generation vaccines against coronavirus disease 2019 (COVID-19) focus on inducing a long-lasting immune response against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its emerging variants. To achieve this, antigens other than spike proteins have been proposed, an...

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Main Authors: Noe Juvenal Mendoza-Ramírez, Julio García-Cordero, Gabriela Hernández-Galicia, Nicole Justine Moreno-Licona, Jesus Hernandez, Carlos Cabello-Gutierrez, Joaquín Alejandro Zúñiga-Ramos, Edgar Morales-Rios, Sonia Mayra Pérez-Tapia, Vianney Ortiz-Navarrete, Martha Espinosa-Cantellano, David Andrés Fernández-Benavides, Leticia Cedillo-Barrón
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Vaccines
Subjects:
vaccine
nucleocapsid
plasmid DNA
fusion proteins
DNA immunization
Online Access:https://www.mdpi.com/2076-393X/13/2/134
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