Quantification of bactericidal activity using the PATHFAST TB LAM Ag assay during the first 14 days of pulmonary tuberculosis treatment

Quantification of bactericidal activity using the PATHFAST TB LAM Ag assay during the first 14 days of pulmonary tuberculosis treatment

BackgroundTuberculosis (TB) remains a global health challenge. Culture-free, rapid, and quantitative biomarkers to monitor treatment response are critical to accelerate development of better TB treatments. The PATHFAST TB LAM Ag assay (PATHFAST-LAM), a desktop chemiluminescent enzyme immunoassay tha...

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Bibliographic Details
Main Authors: Ayumi Akinaga, Andreas H. Diacon, Remous Ocloo, Atsushi Yanagida, Naofumi Yoda, Masanori Kawasaki, Yongge Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Antibiotics
Subjects:
tuberculosis
treatment monitoring
lipoarabinomannan
biomarker
bacterial load
immunoassay
Online Access:https://www.frontiersin.org/articles/10.3389/frabi.2025.1574688/full
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https://www.frontiersin.org/articles/10.3389/frabi.2025.1574688/full

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