Neurexin1 level in Huntington’s Disease and decreased Neurexin1 in disease progression

Huntington’s disease (HD) is a neurodegenerative disorder characterized by the presence of abnormally expanded polyglutamine tracts in huntingtin protein (HTT). Mutant HTT disrupts synaptic transmission and plasticity, particularly in the striatum and cortex, leading to early dysfunctions, such as a...

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Bibliographic Details
Main Authors: Kyoungjoo Cho, Gyung Whan Kim
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Neuroscience Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0168010224001330
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