The use of pancreatic ductal adenocarcinoma 2D and 3D models to evaluate NDV infection, replication and induced cell death
Abstract The development and testing of cancer therapies, such as oncolytic viro-immunotherapy, starts with 2-dimensional cell culture models, such as monolayers from lab-adapted cell lines. Although 2D models have been valuable, 3-dimensional models such as spheroids and patient-derived organoids (...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-06023-8 |
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