A Pharmacokinetic Study of the Interaction Between Regorafenib and Paracetamol in Male Rats

A Pharmacokinetic Study of the Interaction Between Regorafenib and Paracetamol in Male Rats

<b>Background</b>: In clinical practice, the prevalent problem of polypharmacy could result in increased risks of drug–drug interactions. Regorafenib (REG) is commonly co-administered with paracetamol (PA) as a treatment protocol in cancer patients with pain therapy. <b>Purpose<...

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Bibliographic Details
Main Authors: Agnieszka Karbownik, Danuta Szkutnik-Fiedler, Filip Otto, Anna Wolc, Tomasz Grabowski, Zuzanna Maciejewska, Aleksandra Borycka, Edyta Szałek
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Pharmaceutics
Subjects:
drug–drug interaction
pharmacokinetics
regorafenib
paracetamol
Online Access:https://www.mdpi.com/1999-4923/16/11/1387
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