Spatial transcriptomics reveals tumor microenvironment heterogeneity in EBV positive diffuse large B cell lymphoma

Abstract Accumulating research suggests that Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma (EBV+DLBCL) is associated with immune dysfunction and tumor microenvironment (TME) heterogeneity. While the prognostic role of the TME in EBV-DLBCL is established, its impact on EBV+DLBCL survival...

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Bibliographic Details
Main Authors: Mei-yao He, Meng Liu, Jiayin Yuan, Jin Lv, Wei Li, Qianwen Yan, Yujiao Tang, Luyi Wang, Li Guo, Fang Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-00410-x
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