Early Determination of Tacrolimus Concentration–Dose Ratio Identifies Risk of Allograft Loss in Kidney Transplantation

Introduction: Fast tacrolimus–metabolizing kidney transplant recipients (KTRs) (i.e., tacrolimus trough-level/total daily dose [C0/D < 1.05]) have poorer allograft function; however, their identification in a real-life setting is challenging. We investigated the reproducibility of tacrolimus meta...

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Main Authors: Christophe Masset, Marine Lorent, Clarisse Kerleau, Claire Garandeau, Aurélie Houzet, Simon Ville, Diego Cantarovich, Gilles Blancho, Magali Giral, Jacques Dantal, Julien Branchereau, Agnès Chapelet, Florent Delbos, Clément Deltombe, Lucile Figueres, Charles Ronsin, Thibault Letellier, Clémence Petit, Caroline Gourraud-Vercel, Laurent Nicolet, Christine Kandel-Aznar, Ismaël Chelghaf, Aurélie Meurette, Karine Renaudin, Alexandre Walencik
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Kidney International Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925001032
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