PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP

PA28γ promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP

Proteasome activator 28γ (PA28γ) plays a critical role in malignant progression of various tumors, however, its role and regulation are not well understood. Here, using oral squamous cell carcinoma (OSCC) as the main research model, and combining co-immunoprecipitation (Co-IP), proximity ligation as...

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Bibliographic Details
Main Authors: Jiongke Wang, Yujie Shi, Ying Wang, Yingqiang Shen, Huan Liu, Silu Sun, Yimei Wang, Xikun Zhou, Yu Zhou, Xin Zeng, Jing Li, Qianming Chen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-07-01
Series:eLife
Subjects:
oral squamous cell carcinoma
PA28γ
C1QBP
protein‒protein interactions
mitochondria
oxidative phosphorylation
Online Access:https://elifesciences.org/articles/101244
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