Exposure to per- and poly-fluoroalkyl substances in association to later occurrence of type 2 diabetes and metabolic pathway dysregulation in a multiethnic US populationResearch in context

Exposure to per- and poly-fluoroalkyl substances in association to later occurrence of type 2 diabetes and metabolic pathway dysregulation in a multiethnic US populationResearch in context

Summary: Background: Growing evidence suggests that exposure to per- and polyfluoroalkyl substances (PFAS) are linked to an increased risk of type 2 diabetes (T2D); however, the effect of PFAS mixtures and underlying mechanisms are not well understood. We examined the associations between exposure...

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Main Authors: Vishal Midya, Meizhen Yao, Elena Colicino, Dinesh Barupal, Xiangping Lin, Chris Gennings, Leda Chatzi, Veronica Wendy Setiawan, Ruth J.F. Loos, Ryan W. Walker, Douglas I. Walker, Damaskini Valvi
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:EBioMedicine
Subjects:
Exposomics
Type 2 diabetes
Per-and polyfluoroalkyl substances
Metabolomics
Exposure mixture
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425002828
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