Clinical outcomes of EGFR-TKI in advanced lung squamous cell carcinoma and EGFR-TKI remodel tumor immune microenvironment

Clinical outcomes of EGFR-TKI in advanced lung squamous cell carcinoma and EGFR-TKI remodel tumor immune microenvironment

Background Clinical data is scarce in epidermal growth factor receptor (EGFR)-mutated lung squamous cell carcinoma (LUSC), and the resistance mechanisms to EGFR-tyrosine kinase inhibitor (TKI) is rarely studied. This study aimed to assess the efficacy of EGFR-TKI treatment in EGFR-mutated LUSC patie...

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Bibliographic Details
Main Authors: Zhixin Chen, Jiali Gong, Jing Chen, Lan Yang, Shumin Hu, Lingru Chen, Hongyang Lu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
Subjects:
Lung squamous cell carcinoma
EGFR mutation
resistance mechanism
tumor immune microenvironment
therapy
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2025.2488109
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https://www.tandfonline.com/doi/10.1080/07853890.2025.2488109

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