TELO-SCOPE study: a randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosis

TELO-SCOPE study: a randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosis

Introduction Recent discoveries have identified shortened telomeres and related mutations in people with pulmonary fibrosis (PF). There is evidence to suggest that androgens, including danazol, may be effective in lengthening telomeres in peripheral blood cells. This study aims to assess the safety...

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Main Authors: Tamera J Corte, Adam Jaffe, Christopher Grainge, Jeremy Wrobel, Hiran Selvadurai, Stephanie T Yerkovich, Daniel C Chambers, Maxine Tan, Ian Glaspole, Peter Hopkins, Paul N Reynolds, Hilda A Pickett, Nicole S Goh, John A Mackintosh, Maria Pietsch, Viviana Lutzky, Debra Enever, Sandra Bancroft, Simon H Apte, Joanne L Dickinson
Format: Article
Language:English
Published: BMJ Publishing Group 2021-01-01
Series:BMJ Open Respiratory Research
Online Access:https://bmjopenrespres.bmj.com/content/8/1/e001127.full
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https://bmjopenrespres.bmj.com/content/8/1/e001127.full

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