Pre-ART levels of inflammation and coagulation markers are strong predictors of death in a South African cohort with advanced HIV disease.

Pre-ART levels of inflammation and coagulation markers are strong predictors of death in a South African cohort with advanced HIV disease.

<h4>Background</h4>Levels of high-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6), and D-dimer predict mortality in HIV patients on antiretroviral therapy (ART) with relatively preserved CD4+ T cell counts. We hypothesized that elevated pre-ART levels of these markers among...

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Main Authors: Lotty Ledwaba, Jorge A Tavel, Paul Khabo, Patrick Maja, Jing Qin, Phumele Sangweni, Xiao Liu, Dean Follmann, Julia A Metcalf, Susan Orsega, Beth Baseler, James D Neaton, H Clifford Lane, Project Phidisa Biomarkers Team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0024243&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0024243&type=printable

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