YAP charge patterning mediates signal integration through transcriptional co-condensates

Abstract Transcription factor dynamics are used to selectively engage gene regulatory programs. Biomolecular condensates have emerged as an attractive signaling module in this process, but the underlying mechanisms are not well-understood. Here, we probe the molecular basis of YAP signal integration...

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Bibliographic Details
Main Authors: Kirstin Meyer, Klaus Yserentant, Rasmi Cheloor-Kovilakam, Kiersten M. Ruff, Chan-I Chung, Xiaokun Shu, Bo Huang, Orion D. Weiner
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62157-3
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