Genetic Predisposition to Hepatocarcinogenesis in Inbred and Outbred Mouse Lines Selected for High or Low Inflammatory Response

Genetic Predisposition to Hepatocarcinogenesis in Inbred and Outbred Mouse Lines Selected for High or Low Inflammatory Response

AIRmax and AIRmin mouse strains phenotypically selected for high and low acute inflammatory responsiveness (AIR) are, respectively, susceptible or resistant to developing hepatocellular carcinoma (HCC) induced by the chemical carcinogens urethane and diethylnitrosamine (DEN). Early production of TNF...

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Main Authors: Lilian Rego de Carvalho, Andrea Borrego, José Ricardo Jensen, Wafa Hanna Koury Cabrera, Aline Marques Santos, Orlando Garcia Ribeiro, Nancy Starobinas, Marcelo De Franco, Tommaso A. Dragani, Giacomo Manenti, Olga Célia Martinez Ibañez
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/5298792
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