Current efficacy of immune checkpoint inhibitors in microsatellite unstable colorectal cancer and potential biomarkers
Microsatellite unstable (MSI) colorectal cancer (CRC) tumors have a high mutational load (particularly frame-shift mutations) that creates numerous neoantigens that are presented to major histocompatibility complex molecules and recognized by T cells. Consequently, MSI tumors have a higher presence...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Open Exploration Publishing Inc.
2025-02-01
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| Series: | Exploration of Digestive Diseases |
| Subjects: | |
| Online Access: | https://www.explorationpub.com/uploads/Article/A100564/100564.pdf |
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