Influence of hybridization probe capture and amplicon library construction methods on HLA genotyping resolution level

Influence of hybridization probe capture and amplicon library construction methods on HLA genotyping resolution level

[Objective] To compare next generation sequencing (NGS) library construction technology between probe hybridization capture and amplicon methods, and analyze the influencing factors of HLA genotyping resolution level and its prospects in clinical applications. [Methods] A total of 207 clinical sampl...

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Bibliographic Details
Main Authors: YUAN Xiaoni, ZHANG Tengteng, LI Yang, JIANG Xue, YANG Tianjie, BAO Xiaojing, HE Jun
Format: Article
Language:zho
Published: Institute of Blood Transfusion of Chinese Academy of Medical Sciences 2025-03-01
Series:Zhongguo shuxue zazhi
Subjects:
hla
next generation sequencing
allele
clinical application
Online Access:https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.03.001&lang=en
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https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.03.001&lang=en

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