Quercitrin, the primary active ingredient of Albizia julibrissin Durazz. flowers, alleviates methamphetamine-induced hepatotoxicity through a mitochondria-mediated apoptosis pathway

Quercitrin, the primary active ingredient of Albizia julibrissin Durazz. flowers, alleviates methamphetamine-induced hepatotoxicity through a mitochondria-mediated apoptosis pathway

Background and purposeMethamphetamine (METH), a synthetic psychostimulant and highly addictive drug, could cause depression and acute liver injury. There have been few studies on the mechanism by which METH induces liver damage and on how to alleviate METH-induced hepatic toxicities. Albizzia julibr...

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Bibliographic Details
Main Authors: Dan Wu, Bo Xie, Jing Li, Zhangang Xiao, Jing Shen, Xu Wu, Mingxing Li, Qin Sun, Hongping Shen, Xiaobing Li, Yong Dai, Yueshui Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
quercitrin
oxidative damage
hepatotoxicity
ROS
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1482172/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1482172/full

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