Genomic and micro-environmental insights into drug resistance in colorectal cancer liver metastases

Abstract Background Colorectal cancer (CRC) is known for its high heterogeneity, with liver metastases significantly impairing survival outcomes. Understanding the tumor microenvironment (TME) and genomic alterations in metastatic sites is crucial for developing personalized therapies that overcome...

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Bibliographic Details
Main Authors: Junjie Kuang, Jun Li, Siwei Zhou, Yi Li, Jinbo Lin, Weizhen Huang, Xia Yuan
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-01976-8
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