Voluntarily wheel running protects doxorubicin-induced kidney injury by inhibiting oxidative stress through mitochondrial function.

<h4>Background</h4>Doxorubicin (DOX) has a broad anticancer spectrum and precise anticancer effects, but its clinical application is limited by severe multiorgan toxicity, among which nephrotoxicity is one of the main adverse reactions. In this study, the protective effect of voluntary w...

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Bibliographic Details
Main Authors: Xin Jiang, Zeyu Wang, Longyun Wang, Yuqi Wang, Lijing Zhao, Hongyu Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0321121
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