Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis

Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis

Peripheral nerve injury causes severe neuroinflammation and has become a global medical challenge. Previous research has demonstrated that porcine decellularized nerve matrix hydrogel exhibits excellent biological properties and tissue specificity, highlighting its potential as a biomedical material...

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Bibliographic Details
Main Authors: Rui Li, Jianquan Liu, Liuxun Li, Guotian Luo, Xinrong Yuan, Shichao Shen, Yongpeng Shi, Jianlong Wu, Bin Yan, Lei Yang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2026-03-01
Series:Neural Regeneration Research
Subjects:
anti-inflammatory reaction
macrophage polarization
neuroinflammation
peripheral nerve injury
porcine decellularized nerve matrix hydrogel
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-00302
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https://journals.lww.com/10.4103/NRR.NRR-D-24-00302

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