Using poly-N-acetyl glucosamine gel matrix to deliver IL-12 with anti-schistosomasis vaccination

Using poly-N-acetyl glucosamine gel matrix to deliver IL-12 with anti-schistosomasis vaccination

Background: Interleukin (IL)-12 is a potential adjuvant in a variety of diseases including schistosomiasis. The clinical use of IL-12, however, is limited by the toxicity associated with its systemic administration. We have developed a novel delivery system (designated F2 gel matrix) composed of po...

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Bibliographic Details
Main Authors: Mohamed Labib Salem, Wael Y Attia, Yousry E Al-Bolkiny, Ismail M Al-Sharkawi, Marina Demcheva, John Vournakis
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2010-05-01
Series:Journal of Infection in Developing Countries
Subjects:
Cytokines
IL-12
Paracrine treatment
Schistosoma mansoni
SWAP
Systemic treatment
Online Access:https://jidc.org/index.php/journal/article/view/541
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https://jidc.org/index.php/journal/article/view/541

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