Discovery and molecular characterization of a potent thiazolyl-pyrazole hybrid targeting EGFR for breast cancer therapy
Abstract Herein, a novel compound 2-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazolylidene)-3-phenylthiazolidin-5-one )2(was synthesized and reacted with different aromatic aldehydes 3a-f via Knoevenagel condensation reaction to give the corresponding 4-arylidene-2-(5-oxo-1,5-dihydro-4H-pyrazol-4-yl...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-07261-6 |
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