Comprehensive multi-omics and machine learning framework for glioma subtyping and precision therapeutics

Abstract Glioma is a highly heterogeneous and aggressive brain tumour that demands an integrated understanding of its molecular and immunological landscape. We collected multi-omics data from 575 TCGA diffuse-glioma patients (156 IDH-wild-type WHO-grade 4 glioblastomas and 419 IDH-mutant WHO-grade 2...

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Bibliographic Details
Main Authors: Yi Ding, Zhaiyue Xu, Wenjing Hu, Peng Deng, Mian Ma, Jiandong Wu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-09742-0
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