Granulocyte-Macrophage Colony-Stimulating Factor Inhibition Ameliorates Innate Immune Cell Activation, Inflammation, and Salt-Sensitive Hypertension

Granulocyte-Macrophage Colony-Stimulating Factor Inhibition Ameliorates Innate Immune Cell Activation, Inflammation, and Salt-Sensitive Hypertension

Hypertension (HTN) is a major contributor to global morbidity and manifests in several variants, including salt-sensitive hypertension (SSHTN). SSHTN is defined by an increase in blood pressure (BP) in response to high dietary salt, and is associated with heightened cardiovascular risk, renal damage...

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Bibliographic Details
Main Authors: Hannah L. Smith, Bethany L. Goodlett, Gabriella C. Peterson, Emily N. Zamora, Ava R. Gostomski, Brett M. Mitchell
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
granulocyte-macrophage colony-stimulating factor
salt-sensitive hypertension
CD38
m1 macrophages
type 2-conventional dendritic cells
Online Access:https://www.mdpi.com/2073-4409/14/15/1144
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