Predicting survival in prospective clinical trials using weakly-supervised QSP
Abstract Quantitative systems pharmacology (QSP) models of cancer immunity provide mechanistic insights into cellular dynamics and drug effects that are difficult to study clinically. However, their inability to predict patient survival mechanistically limits their utility in anti-cancer drug develo...
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| Main Authors: | Matthew West, Kenta Yoshida, Jiajie Yu, Vincent Lemaire |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | npj Precision Oncology |
| Online Access: | https://doi.org/10.1038/s41698-025-00898-6 |
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