Potential therapeutic effects of ibudilast and retinoic acid against cuprizone-induced behavioral and biochemical changes in mouse brain

Potential therapeutic effects of ibudilast and retinoic acid against cuprizone-induced behavioral and biochemical changes in mouse brain

Ibudilast (IBD) is a new drug that has been released as treatment for multiple sclerosis (MS). Retinoic acid (RA), a metabolite of vitamin A, is known for its pro-regenerative and anti-inflammatory properties, therefore, it has been suggested as a supplementary treatment for MS. The objective of thi...

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Main Authors: Kholoud A. Alyami, Gadah A. Alshahrany, Kholoud M. Al-Otaibi, Mohammad Z. Alam, Badrah S. Alghamdi, Hadeil M. Alsufiani, Nouf O. Alshareef, Hanna M. Alhoraibi, Sahar A. Alkhodair, Ulfat M. Omar
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
multiple sclerosis
ibudilast
retinoic acid
vitamin A
cuprizone
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2025.1567226/full
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https://www.frontiersin.org/articles/10.3389/fnmol.2025.1567226/full

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