HTLV‐1 infected T cells cause bone loss via small extracellular vesicles

HTLV‐1 infected T cells cause bone loss via small extracellular vesicles

Abstract Adult T cell leukaemia (ATL), caused by infection with human T‐ lymphotropic virus type 1 (HTLV‐1), is often complicated by hypercalcemia and osteolytic lesions. Therefore, we studied the communication between patient‐derived ATL cells (ATL‐PDX) and HTLV‐1 immortalized CD4+ T cell lines (HT...

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Main Authors: Nitin Kumar Pokhrel, Amanda R. Panfil, Haniya Habib, Shamreethaa Seeniraj, Ancy Joseph, Daniel Rauch, Linda Cox, Robert Sprung, Petra Erdmann Gilmore, Qiang Zhang, Robert Reid Townsend, Lianbo Yu, Ayse Selen Yilmaz, Rajeev Aurora, William Park, Lee Ratner, Katherine N. Weilbaecher, Deborah J. Veis
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Journal of Extracellular Vesicles
Subjects:
adult T cell leukaemia
extracellular vesicles
osteoclast
osteolysis
proteomics
Online Access:https://doi.org/10.1002/jev2.12516
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https://doi.org/10.1002/jev2.12516

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