Selective Glucocorticoid Receptor (GR-II) Antagonist Reduces Body Weight Gain in Mice

Previous research has shown that mifepristone can prevent and reverse weight gain in animals and human subjects taking antipsychotic medications. This proof-of-concept study tested whether a more potent and selective glucocorticoid receptor antagonist could block dietary-induced weight gain and incr...

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Bibliographic Details
Main Authors: Tomoko Asagami, Joseph K. Belanoff, Junya Azuma, Christine M. Blasey, Robin D. Clark, Philip S. Tsao
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Nutrition and Metabolism
Online Access:http://dx.doi.org/10.1155/2011/235389
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