Histone lactylation as a driver of metabolic reprogramming and immune evasion
Lactate is the end product of glycolysis, and extensive research has shown that lactate participates in various pathophysiological processes. Along with associated hydrogen ions, lactate typically functions as an immunosuppressive negative factor and plays a crucial role in tumor metabolic reprogram...
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| Main Authors: | Cai Qiaoting, Deng Wei, Zou Yutian, Chen Zhe-Sheng, Tang Hailin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2024-12-01
|
| Series: | Medical Review |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/mr-2024-0091 |
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