Histone lactylation as a driver of metabolic reprogramming and immune evasion

Lactate is the end product of glycolysis, and extensive research has shown that lactate participates in various pathophysiological processes. Along with associated hydrogen ions, lactate typically functions as an immunosuppressive negative factor and plays a crucial role in tumor metabolic reprogram...

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Bibliographic Details
Main Authors: Cai Qiaoting, Deng Wei, Zou Yutian, Chen Zhe-Sheng, Tang Hailin
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Medical Review
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Online Access:https://doi.org/10.1515/mr-2024-0091
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