Isoproterenol mechanisms in inducing myocardial fibrosis and its application as an experimental model for the evaluation of therapeutic potential of phytochemicals and pharmaceuticals

Abstract Cardiac injury initiates repair mechanisms and results in cardiac remodeling and fibrosis, which appears to be a leading cause of cardiovascular diseases. Cardiac fibrosis is characterized by the accumulation of extracellular matrix proteins, mainly collagen in the cardiac interstitium. Man...

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Bibliographic Details
Main Authors: Lujain Bader Eddin, Mohamed Fizur Nagoor Meeran, Niraj Kumar Jha, Samer N. Goyal, Shreesh Ojha
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Animal Models and Experimental Medicine
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Online Access:https://doi.org/10.1002/ame2.12496
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