Mechanism Insight of Cell Death Signaling by Thymol Derivatives on Trypanosomatidae Protozoan Parasites

Mechanism Insight of Cell Death Signaling by Thymol Derivatives on Trypanosomatidae Protozoan Parasites

Leishmaniasis and Chagas disease are parasitic diseases considered to be among the most important neglected diseases, with implications for both developed and developing countries. Currently, there are no effective therapeutic treatments for these diseases due to challenges in drug administration, h...

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Main Authors: Amani Omrani, Meriam Ben Youssef, Ines Sifaoui, Eduardo Hernández-Álvarez, Carlos J. Bethencourt-Estrella, Isabel L. Bazzocchi, Hichem Sebai, Jacob Lorenzo-Morales, Ignacio A. Jiménez, José E. Piñero
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Antibiotics
Subjects:
thymol derivatives
<i>Leishmania amazonensis</i>
<i>Trypanosoma cruzi</i>
structure–activity relationship
mechanism of action
drug-likeness
Online Access:https://www.mdpi.com/2079-6382/14/4/383
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