Two-stage re-estimation adaptive design: a simulation study

<p><strong>Background:</strong> adaptive clinical trial design has been proposed as a promising new approach to improve the drug discovery process. Among the many options available, adaptive sample size re-estimation is of great interest mainly because of its ability to avoid a lar...

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Bibliographic Details
Main Authors: Francesca Galli, Luigi Mariani
Format: Article
Language:English
Published: Milano University Press 2013-10-01
Series:Epidemiology, Biostatistics and Public Health
Online Access:http://ebph.it/article/view/8862
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