Photochemically synthesized gold nanoparticles conjugated with Boswellic acid inhibit alpha synuclein aggregation and delay fibrillation kinetics

Photochemically synthesized gold nanoparticles conjugated with Boswellic acid inhibit alpha synuclein aggregation and delay fibrillation kinetics

Abstract Neurodegenerative disorders are characterised by the gradual degeneration and death of neurons in distinct brain regions. In Parkinson’s disease (PD), a key pathological hallmark is the aggregation of misfolded α-synuclein (α-Syn) into neurotoxic fibrils. Although natural products such as B...

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Bibliographic Details
Main Authors: Masoumeh Gharb, Farima Mozafari, Payam Arghavani, Ali Akbar Saboury, Gholamhossein Riazi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
α-synuclein
Boswellic acids
Gold nanoparticle
Protein fibrillation
Online Access:https://doi.org/10.1038/s41598-025-11107-6
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https://doi.org/10.1038/s41598-025-11107-6

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