Comprehensive characterization of multi-omics landscapes between gut microbial metabolites and the druggable genome in sepsis

BackgroundSepsis is a life-threatening condition with limited therapeutic options. Emerging evidence implicates gut microbial metabolites in modulating host immunity, but the specific interactions between these metabolites and host druggable targets remain poorly understood.MethodsWe utilized a syst...

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Bibliographic Details
Main Authors: Jun Liu, Tong Li, Li Xin, Xingyu Li, Jianbo Zhang, Peng Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1597676/full
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