Investigation on the Interactions of NiCR and NiCR-2H with DNA

We report here a biophysical and biochemical approach to determine the differences in interactions of NiCR and NiCR-2H with DNA. Our goal is to determine whether such interactions are responsible for the recently observed differences in their cytotoxicity toward MCF-7 cancer cells. Viscosity measure...

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Bibliographic Details
Main Authors: Priyanka Chitranshi, Chang-Nan Chen, Patrick R. Jones, Jesika S. Faridi, Liang Xue
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2010/619436
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