Large-scale biosynthetic analysis of human microbiomes reveals diverse protective ribosomal peptides

Abstract The human microbiome produces diverse metabolites that influence host health, yet the chemical landscape of ribosomally synthesized and post-translationally modified peptides (RiPPs)—a versatile class of bioactive compounds—remains underexplored. Here, we conduct a large-scale biosynthetic...

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Bibliographic Details
Main Authors: Jian Zhang, Dengwei Zhang, Yi Xu, Junliang Zhang, Runze Liu, Ying Gao, Yuqi Shi, Peiyan Cai, Zheng Zhong, Beibei He, Xuechen Li, Hongwei Zhou, Muxuan Chen, Yong-Xin Li
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58280-w
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