Viral polymerase-host interaction analysis reveals that the association between avian NUP93 and PB1 promotes H5N6 avian influenza virus replication

Viral polymerase-host interaction analysis reveals that the association between avian NUP93 and PB1 promotes H5N6 avian influenza virus replication

ABSTRACT The H5N6 avian influenza virus, a highly pathogenic strain, poses a significant threat to poultry production and public health. The RNA-dependent RNA polymerase (comprising PB1, PB2, and PA proteins) and nucleoprotein of highly pathogenic avian influenza viruses interact with avian host pro...

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Bibliographic Details
Main Authors: Lei Cao, Ting Wang, Peilei Ren, Chuxing Cheng, Haiying Mao, Xianfeng Hui, Xian Lin, Xiaotong Hu, Xiaomei Sun, Kun Huang, Meilin Jin
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:Microbiology Spectrum
Subjects:
H5N6 avian influenza virus
host protein
polymerase
PB1
NUP93
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03120-24
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https://journals.asm.org/doi/10.1128/spectrum.03120-24

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