Significant Reduction of Chenodeoxycholic Acid and Glycochenodeoxycholic Acid in the Elderly with Severe COVID-19

Significant Reduction of Chenodeoxycholic Acid and Glycochenodeoxycholic Acid in the Elderly with Severe COVID-19

Elderly individuals infected with SARS-CoV-2 are at higher risk of developing cytokine storms and severe outcomes, yet specific biomarkers remain unclear. In this study, we investigated the alteration of primary bile acid metabolism in elderly patients with severe COVID-19 using untargeted metabolom...

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Bibliographic Details
Main Authors: Shiyang Liu, Wen Xu, Bo Tu, Zhiqing Xiao, Xue Li, Lei Huang, Xin Yuan, Shengdong Luo, Juanjuan Zhou, Xinxin Yang, Junlian Yang, De Chang, Weiwei Chen, Fu-Sheng Wang
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
CDCA
GCDCA
elderly COVID-19 patients
disease progression
inflammatory response
Online Access:https://www.mdpi.com/2218-273X/15/7/943
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