Single-cell transcriptomic atlas of the chicken cecum reveals cellular responses and state shifts during Eimeria tenella infection

Single-cell transcriptomic atlas of the chicken cecum reveals cellular responses and state shifts during Eimeria tenella infection

Abstract Eimeria tenella (E. tenella) infection is a major cause of coccidiosis in chickens, leading to significant economic losses in the poultry industry due to its impact on the cecum. This study presents a comprehensive single-cell atlas of the chicken cecal epithelium by generating 7,394 cells...

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Main Authors: Jun-Hao Tu, Bo-Gong Liu, Bing-Jin Lin, Hui-Chao Liu, Song-Chang Guo, Qing-Yuan Ouyang, Ling-Zhao Fang, Xi He, Ze-He Song, Hai-Han Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Genomics
Subjects:
Single-cell RNA sequencing (scRNA-seq)
Eimeria tenella
Chicken cecum
Coccidiosis
APOB + enterocytes
Online Access:https://doi.org/10.1186/s12864-025-11302-9
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https://doi.org/10.1186/s12864-025-11302-9

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