Molecular characteristics and cancer immunity of LRP1B and its relationship with the Hedgehog signaling pathway in colorectal cancer

Molecular characteristics and cancer immunity of LRP1B and its relationship with the Hedgehog signaling pathway in colorectal cancer

BackgroundColorectal cancer (CRC) is a malignant tumor of the digestive tract that significantly impacts human health. LDL receptor-related protein 1B (LRP1B) may play a crucial role in tumorigenesis and disease progression.MethodsWe performed a comparative analysis of differential gene expression,...

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Bibliographic Details
Main Authors: Yuan Liu, Yang Zhong, Yaodong Sang, Siqiang Zhu, Kang Xu, Xingyu Zhu, Xiaoling Cui, Xinyu Liu, Xiaohan Wang, Hao Chen, Changqing Jing, Wei Chong, Leping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
colorectal cancer (CRC)
LRP1B
hedgehog (Hh) signaling pathway
immune cell infiltration
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567102/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567102/full

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