Characterization of within-host Plasmodium falciparum diversity using next-generation sequence data.

Characterization of within-host Plasmodium falciparum diversity using next-generation sequence data.

Our understanding of the composition of multi-clonal malarial infections and the epidemiological factors which shape their diversity remain poorly understood. Traditionally within-host diversity has been defined in terms of the multiplicity of infection (MOI) derived by PCR-based genotyping. Massive...

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Main Authors: Sarah Auburn, Susana Campino, Olivo Miotto, Abdoulaye A Djimde, Issaka Zongo, Magnus Manske, Gareth Maslen, Valentina Mangano, Daniel Alcock, Bronwyn MacInnis, Kirk A Rockett, Taane G Clark, Ogobara K Doumbo, Jean Bosco Ouédraogo, Dominic P Kwiatkowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0032891&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0032891&type=printable

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