IGF2BP3 as a Novel Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma

IGF2BP3 as a Novel Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma

RNA-binding proteins (RBPs), particularly IGF2BP3, play critical but underexplored roles in lung adenocarcinoma (LUAD). This study investigated IGF2BP3′s clinical and functional significance using single-cell/RNA sequencing, validated by qPCR, Western blot, and immunohistochemistry. The results show...

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Main Authors: Feiming Hu, Chenchen Hu, Yuanli He, Lin Guo, Yuanjie Sun, Chenying Han, Xiyang Zhang, Junyi Ren, Jinduo Han, Jing Wang, Junqi Zhang, Yubo Sun, Sirui Cai, Dongbo Jiang, Kun Yang, Shuya Yang
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Series:Cells
Subjects:
IGF2BP3
lung adenocarcinoma
therapeutic target
tumor immune microenvironment
prognostic biomarker
Online Access:https://www.mdpi.com/2073-4409/14/15/1222
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https://www.mdpi.com/2073-4409/14/15/1222

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